

ROCK 通道抑制剂-Blebbistatin
Nuwacell® Blebbistatin(RP01008)是广泛应用的非肌肉肌球蛋白II型ATP酶抑制剂。Blebbistatin作用于ROCK-myosinII信号通路,可以阻止多功能干细胞因分离导致的凋亡,在不影响hPSC的自我更新或者多潜能特性的前提下改善分离的hPSC的存活率和克隆效率。
产品 | 规格 | 货号 | 存储条件 |
Nuwacell® Blebbistatin |
3mg(1mL) | RP01008 | -20℃ |

终浓度2.5μM的Blebbistatin传代hiPSC(P18)形态图片。
A、B、C:分别为培养第1、2、3天时,显微镜下hiPSC形态图示。标尺:200μm。

-
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelialcells in rodent model- the first pre-clinical study for safety and efficacy in ChinaHang Zhang,et al.Ann Transl Med 2021(IF 3.616).
-
Establishment of an induced pluripotent stem cell line from a patient with hereditary transthyretin amyloidosis carrying transthyretin (TTR) mutation p.Phe53Val2020. He Shan, et al. Stem Cell Research(IF 1.587).
-
Establishment of an induced pluripotent stem cell line PUMCHi004-A from a hereditary transthyretin amyloid cardiomyopathy patient with transthyretin (TTR) p.Asp38Asn mutation2020. He Shan , et al. Stem Cell Research(IF 1.587).
更多引用文献,请拨打400 888 3920详细咨询